Ezrin phosphorylation on tyrosine 477 regulates invasion and metastasis of breast cancer cells

Background The membrane cytoskeletal crosslinker, ezrin, a member of the ERM family of proteins, is frequently over-expressed in human breast cancers, and is required for motility and invasion of epithelial cells. Our group previously showed that ezrin acts co-operatively with the non-receptor tyros...

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Main Authors: Mak, Hannah (Author), Naba, Alexandra (Contributor), Varma, Sonal (Author), Schick, Colleen (Author), Day, Andrew (Author), SenGupta, Sandip K (Author), Arpin, Monique (Author), Elliott, Bruce E (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: BioMed Central Ltd., 2012-07-19T20:27:19Z.
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