UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on protein-DNA interactions

The Universal PBM Resource for Oligonucleotide-Binding Evaluation (UniPROBE) database is a centralized repository of information on the DNA-binding preferences of proteins as determined by universal protein-binding microarray (PBM) technology. Each entry for a protein (or protein complex) in UniPROB...

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Bibliographic Details
Main Authors: Bulyk, Martha L. (Contributor), Robasky, Kimberly (Author)
Other Authors: Harvard University- (Contributor)
Format: Article
Language:English
Published: Oxford University Press (OUP), 2012-06-01T17:56:13Z.
Subjects:
Online Access:Get fulltext
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100 1 0 |a Bulyk, Martha L.  |e author 
100 1 0 |a Harvard University-  |e contributor 
100 1 0 |a Bulyk, Martha L.  |e contributor 
100 1 0 |a Bulyk, Martha L.  |e contributor 
700 1 0 |a Robasky, Kimberly  |e author 
245 0 0 |a UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on protein-DNA interactions 
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856 |z Get fulltext  |u http://hdl.handle.net/1721.1/70988 
520 |a The Universal PBM Resource for Oligonucleotide-Binding Evaluation (UniPROBE) database is a centralized repository of information on the DNA-binding preferences of proteins as determined by universal protein-binding microarray (PBM) technology. Each entry for a protein (or protein complex) in UniPROBE provides the quantitative preferences for all possible nucleotide sequence variants ('words') of length k ('k-mers'), as well as position weight matrix (PWM) and graphical sequence logo representations of the k-mer data. In this update, we describe >130% expansion of the database content, incorporation of a protein BLAST (blastp) tool for finding protein sequence matches in UniPROBE, the introduction of UniPROBE accession numbers and additional database enhancements. The UniPROBE database is available at http://uniprobe.org. 
520 |a National Institutes of Health (U.S.) (grant number R01 HG003985) 
546 |a en_US 
655 7 |a Article 
773 |t Nucleic Acids Research