Endo-Selective Enyne Ring- Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes

Endo-Selective Enyne Ring- Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes

The utility of W-alkylidene complexes for enyne ring-closing metathesis is demonstrated in a direct comparison with Mo-based analogs. Tungsten complexes lead to less alkyne oligomerization and higher levels of endo-selectivity and enantioselectivity.

Bibliographic Details
Main Authors: Zhao, Yu (Contributor), Hoveyda, Amir H. (Author), Schrock, Richard Royce (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society, 2012-04-04T20:00:34Z.
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Description
Summary:The utility of W-alkylidene complexes for enyne ring-closing metathesis is demonstrated in a direct comparison with Mo-based analogs. Tungsten complexes lead to less alkyne oligomerization and higher levels of endo-selectivity and enantioselectivity.
National Institutes of Health (U.S.) (GM-59426)

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