Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome

Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome

Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability. In addition to cognitive deficits, FXS patients exhibit hyperactivity, attention deficits, social difficulties, anxiety, and other autistic-like behaviors. FXS is caused by an expanded CGG trinucleotide repeat in...

Full description

Bibliographic Details
Main Authors: Theriault, Kraig M. (Author), Daheron, Laurence (Author), Loring, Jeanne F. (Author), Sheridan, Steven (Contributor), Reis, Surya A. (Contributor), Zhou, Fen (Contributor), Madison, Jon M. (Contributor), Haggarty, Stephen J. (Contributor)
Other Authors: Broad Institute of MIT and Harvard (Contributor), Massachusetts Institute of Technology. Research Laboratory of Electronics (Contributor), Picower Institute for Learning and Memory (Contributor), Haggarty, Stephen (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2012-02-23T18:15:58Z.
Subjects:
Article
Online Access:Get fulltext

Similar Items

Similar Items