Manganese displacement from Zinpyr-1 allows zinc detection by fluorescence microscopy and magnetic resonance imaging

• Main Authors: You, Youngmin (Contributor), Tomat, Elisa (Contributor), Hwang, Kevin (Contributor), Atanasijevic, Tatjana (Contributor), Nam, Wonwoo (Author), Jasanoff, Alan Pradip (Contributor), Lippard, Stephen J. (Author)
• Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
• Format: Article
• Language: English
• Published: Royal Society of Chemistry, 2011-11-29T17:28:14Z.
• Subjects: Article
• Online Access: Get fulltext

A paramagnetic manganese complex of a fluorescein-based probe affords a dual-modality zinc sensor featuring an improved fluorescence dynamic range and an MRI readout.
National Institute of General Medical Sciences (U.S.) ((Grant GM065519)
SBS Foundation
National Institutes of Health (U.S.) (NIH Grant DP2-OD2441)
Raymond and Beverley Sackler Foundation