Hemodynamic Environments from Opposing Sides of Human Aortic Valve Leaflets Evoke Distinct Endothelial Phenotypes In Vitro

Hemodynamic Environments from Opposing Sides of Human Aortic Valve Leaflets Evoke Distinct Endothelial Phenotypes In Vitro

The regulation of valvular endothelial phenotypes by the hemodynamic environments of the human aortic valve is poorly understood. The nodular lesions of calcific aortic stenosis (CAS) develop predominantly beneath the aortic surface of the valve leaflets in the valvular fibrosa layer. However, the m...

Full description

Bibliographic Details
Main Authors: Weinberg, Eli J. (Contributor), Mack, Peter J. (Contributor), Shoen, Frederick J. (Author), Garcia-Cardena, Guillermo (Author), Kaazempur Mofrad, Mohammad R. (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Schoen, Frederick J. (Contributor)
Format: Article
Language:English
Published: Springer Science + Business Media B.V., 2011-09-14T16:54:09Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items