The Cooperation between hMena Overexpression and HER2 Signalling in Breast Cancer

The Cooperation between hMena Overexpression and HER2 Signalling in Breast Cancer

hMena and the epithelial specific isoform hMena11a are actin cytoskeleton regulatory proteins belonging to the Ena/VASP family. EGF treatment of breast cancer cell lines upregulates hMena/hMena11a expression and phosphorylates hMena11a, suggesting cross-talk between the ErbB receptor family and hMen...

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Main Authors: Di Modugno, Francesca (Author), Mottolese, Marcella (Author), DeMonte, Lucia (Author), Trono, Paola (Author), Terrenato, Irene (Author), Belleudi, Francesca (Author), Torrisi, Maria Rosaria (Author), Alessio, Massimo (Author), Santoni, Angela (Author), Nistico, Paola (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor), Balsamo, Michele (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2011-07-06T18:30:04Z.
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