A quantitative model of transcriptional regulation reveals the influence binding location on expression

A quantitative model of transcriptional regulation reveals the influence binding location on expression

Understanding the mechanistic basis of transcriptional regulation has been a central focus of molecular biology since its inception. New high-throughput chromatin immunoprecipitation experiments have revealed that most regulatory proteins bind thousands of sites in mammalian genomes. However, the fu...

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Bibliographic Details
Main Authors: MacIsaac, Kenzie Daniel (Contributor), Lo, Kinyui Alice (Contributor), Gordon, William (Contributor), Motola, Shmulik (Contributor), Mazor, Tali (Contributor), Fraenkel, Ernest (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2010-08-12T19:51:46Z.
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