Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects
The retinoblastoma tumor-suppressor protein, pRb, is a member of the pocket protein family that includes p107 and p130. These proteins have well-defined roles in regulating entry into and exit from the cell cycle and also have cell cycle-independent roles in facilitating differentiation. Here we inv...
| Main Authors: | , , , , , |
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| Other Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
United States National Academy of Sciences,
2010-05-14T17:03:48Z.
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| Subjects: | |
| Online Access: | Get fulltext |