Inflammation resolution circuits are uncoupled in acute sepsis and correlate with clinical severity

Sepsis is a critical illness characterized by dysregulated inflammatory responses lacking counter-regulation. Specialized proresolving mediators are agonists for antiinflammation and for promoting resolution, and they are protective in preclinical sepsis models. Here, in human sepsis, we mapped reso...

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Main Authors: Jundi, Bakr (Author), Lee, Do-Hyun (Author), Jeon, Hyungkook (Author), Duvall, Melody G (Author), Nijmeh, Julie (Author), Abdulnour, Raja-Elie E (Author), Pinilla-Vera, Mayra (Author), Baron, Rebecca M (Author), Han, Jongyoon (Author), Voldman, Joel (Author), Levy, Bruce D (Author)
Format: Article
Language:English
Published: American Society for Clinical Investigation, 2022-06-30T15:53:10Z.
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