Tumor cell nuclei soften during transendothelial migration
During cancer metastasis, tumor cells undergo significant deformation in order to traverse through endothelial cell junctions in the walls of blood vessels. As cells pass through narrow gaps, smaller than the nuclear diameter, the spatial configuration of chromatin must change along with the distrib...
Main Authors: | Roberts, Anya B (Author), Zhang, Jitao (Author), Raj Singh, Vijay (Author), Nikolić, Miloš (Author), Moeendarbary, Emad (Author), Kamm, Roger D (Author), So, Peter TC (Author), Scarcelli, Giuliano (Author) |
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Format: | Article |
Language: | English |
Published: |
Elsevier BV,
2022-06-15T16:48:18Z.
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Subjects: | |
Online Access: | Get fulltext |
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