Enantioselective Hydroalkenylation of Olefins with Enol Sulfonates Enabled by Dual Copper Hydride and Palladium Catalysis
The catalytic enantioselective synthesis of α-chiral olefins represents a valuable strategy for rapid generation of structural diversity in divergent syntheses of complex targets. Herein, we report a protocol for the dual CuH- and Pd-catalyzed asymmetric Markovnikov hydroalkenylation of vinyl arenes...
Main Authors: | Schuppe, Alexander W (Author), Knippel, James Levi (Author), Borrajo-Calleja, Gustavo M (Author), Buchwald, Stephen L (Author) |
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Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS),
2022-04-25T17:43:14Z.
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Subjects: | |
Online Access: | Get fulltext |
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