Enantioselective Hydroalkenylation of Olefins with Enol Sulfonates Enabled by Dual Copper Hydride and Palladium Catalysis

The catalytic enantioselective synthesis of α-chiral olefins represents a valuable strategy for rapid generation of structural diversity in divergent syntheses of complex targets. Herein, we report a protocol for the dual CuH- and Pd-catalyzed asymmetric Markovnikov hydroalkenylation of vinyl arenes...

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Bibliographic Details
Main Authors: Schuppe, Alexander W (Author), Knippel, James Levi (Author), Borrajo-Calleja, Gustavo M (Author), Buchwald, Stephen L (Author)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2022-04-25T17:43:14Z.
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