Model‐based control for column‐based continuous viral inactivation of biopharmaceuticals

Batch low-pH hold is a common processing step to inactivate enveloped viruses for biologics derived from mammalian sources. Increased interest in the transition of biopharmaceutical manufacturing from batch to continuous operation resulted in numerous attempts to adapt batch low-pH hold to continuou...

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Bibliographic Details
Main Authors: Hong, Moo Sun (Author), Lu, Amos E. (Author), Ou, Rui Wen (Author), Wolfrum, Jacqueline M. (Author), Springs, Stacy L. (Author), Sinskey, Anthony J. (Author), Braatz, Richard D. (Author)
Format: Article
Language:English
Published: Wiley, 2022-02-16T18:37:33Z.
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