Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development

Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development

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Cerebrospinal fluid (CSF) provides vital support for the brain. Abnormal CSF accumulation, such as hydrocephalus, can negatively affect perinatal neurodevelopment. The mechanisms regulating CSF clearance during the postnatal critical period are unclear. Here, we show that CSF K+, accompanied by wate...

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Bibliographic Details
Main Authors: Xu, Huixin (Author), Fame, Ryann M. (Author), Sutin, Jason (Author), Naranjo, Christopher (Author), Syau, Della (Author), Cui, Jin (Author), Shipley, Frederick B. (Author), Vernon, Amanda (Author), Gao, Fan (Author), Yong, Zhang (Author), Holtzman, Michael J. (Author), Heiman, Myriam (Author), Warf, Benjamin C. (Author), Lin, Pei-Yi (Author), Lehtinen, Maria K. (Author)
Other Authors: Picower Institute for Learning and Memory (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Broad Institute of MIT and Harvard (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2021-04-06T15:35:42Z.
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