Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

A safe and effective vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be required to end the coronavirus disease 2019 (COVID-19) pandemic1-8. For global deployment and pandemic control, a vaccine that requires only a single immunization would be optimal. Here we show the...

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Main Authors: Mercado, Noe B. (Author), Zahn, Roland (Author), Wegmann, Frank (Author), Loos, Carolin (Author), Chandrashekar, Abishek (Author), Yu, Jingyou (Author), Liu, Jinyan (Author), Peter, Lauren (Author), McMahan, Katherine (Author), Tostanoski, Lisa H. (Author), He, Xuan (Author), Martinez, David R. (Author), Rutten, Lucy (Author), Bos, Rinke (Author), van Manen, Danielle (Author), Vellinga, Jort (Author), Custers, Jerome (Author), Langedijk, Johannes P. (Author), Kwaks, Ted (Author), Bakkers, Mark J. G. (Author), Zuijdgeest, David (Author), Rosendahl Huber, Sietske K. (Author), Atyeo, Caroline (Author), Fischinger, Stephanie (Author), Burke, John (Author), Feldman, Jared (Author), Hauser, Blake Marie (Author), Caradonna, Timothy M. (Author), Bondzie, Esther A. (Author), Dagotto, Gabriel (Author), Gebre, Makda S. (Author), Hoffman, Emily (Author), Jacob-Dolan, Catherine (Author), Kirilova, Marinela (Author), Li, Zhenfeng (Author), Lin, Zijin (Author), Mahrokhian, Shant H. (Author), Maxfield, Lori F. (Author), Nampanya, Felix (Author), Nityanandam, Ramya (Author), Nkolola, Joseph P. (Author), Patel, Shivani (Author), Ventura, John D. (Author), Verrington, Kaylee (Author), Wan, Huahua (Author), Pessaint, Laurent (Author), Van Ry, Alex (Author), Blade, Kelvin (Author), Strasbaugh, Amanda (Author), Cabus, Mehtap (Author), Brown, Renita (Author), Cook, Anthony (Author), Zouantchangadou, Serge (Author), Teow, Elyse (Author), Andersen, Hanne (Author), Lewis, Mark G. (Author), Cai, Yongfei (Author), Chen, Bing (Author), Schmidt, Aaron G. (Author), Reeves, R. Keith (Author), Baric, Ralph S. (Author), Lauffenburger, Douglas A. (Author), Alter, Galit (Author), Stoffels, Paul (Author), Mammen, Mathai (Author), Van Hoof, Johan (Author), Schuitemaker, Hanneke (Author), Barouch, Dan (Author)
Other Authors: Ragon Institute of MGH, MIT and Harvard (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2021-02-04T17:02:21Z.
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