Spatiotemporal Up-Regulation of Mu Opioid Receptor 1 in Striatum of Mouse Model of Huntington's Disease Differentially Affecting Caudal and Striosomal Regions

Spatiotemporal Up-Regulation of Mu Opioid Receptor 1 in Striatum of Mouse Model of Huntington's Disease Differentially Affecting Caudal and Striosomal Regions

The striatum of humans and other mammals is divided into macroscopic compartments made up of a labyrinthine striosome compartment embedded in a much larger surrounding matrix compartment. Anatomical and snRNA-Seq studies of the Huntington's disease (HD) postmortem striatum suggest a preferentia...

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Main Authors: Morigaki, Ryoma (Author), Lee, Jannifer (Author), Yoshida, Tomoko (Author), Wuethrich, Christian (Author), Hu, Dan (Author), Crittenden, Jill R (Author), Friedman, Alexander (Author), Kubota, Yasuo (Author), Graybiel, Ann M (Author)
Other Authors: McGovern Institute for Brain Research at MIT (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor)
Format: Article
Language:English
Published: Frontiers Media SA, 2021-02-03T21:17:59Z.
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