Deuteriodifluoromethylation and gem‐Difluoroalkenylation of Aldehydes Using ClCF2H in Continuous Flow
The deuteriodifluoromethyl group (CF₂D) represents a challenging functional group due to difficult deuterium incorporation and unavailability of precursor reagents. Herein, we report the use of chlorodifluoromethane (ClCF₂H) gas in the continuous flow deuteriodifluoromethylation and gem-difluoroalke...
Main Authors: | Fu, Wai Chung (Author), Jamison, Timothy F (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry (Contributor) |
Format: | Article |
Language: | English |
Published: |
Wiley,
2020-11-25T23:00:02Z.
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Subjects: | |
Online Access: | Get fulltext |
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