Molecular basis for catabolism of the abundant metabolite trans-4-hydroxy-L-proline by a microbial glycyl radical enzyme
The glycyl radical enzyme (GRE) superfamily utilizes a glycyl radical cofactor to catalyze difficult chemical reactions in a variety of anaerobic microbial metabolic pathways. Recently, a GRE, trans-4-hydroxy-L-proline (Hyp) dehydratase (HypD), was discovered that catalyzes the dehydration of Hyp to...
| Main Authors: | , , , , , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications, Ltd,
2020-11-10T22:45:06Z.
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| Subjects: | |
| Online Access: | Get fulltext |