Using Carbon Dioxide as a Building Block in Continuous Flow Synthesis

Carbon dioxide (CO₂) is an attractive building block for organic synthesis that is environmentally friendly. Continuous flow technologies have enabled C−O and C−C bond forming reactions with CO₂ that previously were either low‐yielding or impossible in batch to afford value‐added chemicals. This rev...

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Bibliographic Details
Main Authors: Seo, Hyowon (Author), Nguyen, Long V. (Author), Jamison, Timothy F (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Wiley, 2020-10-15T21:37:18Z.
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Online Access:Get fulltext
Description
Summary:Carbon dioxide (CO₂) is an attractive building block for organic synthesis that is environmentally friendly. Continuous flow technologies have enabled C−O and C−C bond forming reactions with CO₂ that previously were either low‐yielding or impossible in batch to afford value‐added chemicals. This review describes recent advances in continuous flow as an enabling strategy in utilizing CO₂ as a C₁ building block in chemical synthesis.