A unique model for SDH-deficient GIST: an endocrine-related cancer

A unique model for SDH-deficient GIST: an endocrine-related cancer

We describe a unique patient-derived xenograft (PDX) and cell culture model of succinate dehydrogenase-deficient gastrointestinal stromal tumor (SDH-deficient GIST), a rare mesenchymal tumor that can occur in association with paragangliomas in hereditary and non-hereditary syndromes. This model is p...

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Bibliographic Details
Main Authors: Sikes, Hadley D. (Author), Langford, Troy F. (Author), Stein, Kassi Taylor (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Bioscientifica, 2020-07-15T13:04:50Z.
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