A Bayesian framework for high-throughput T cell receptor pairing

A Bayesian framework for high-throughput T cell receptor pairing

Motivation: The study of T cell receptor (TCR) repertoires has generated new insights into immune system recognition. However, the ability to robustly characterize these populations has been limited by technical barriers and an inability to reliably infer heterodimeric chain pairings for TCRs. Resul...

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Bibliographic Details
Main Authors: Holec, Patrick V (Author), Berleant, Joseph (Author), Bathe, Mark (Author), Birnbaum, Michael E (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Oxford University Press (OUP), 2020-07-13T17:58:43Z.
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