Application of CRISPR genetic screens to investigate neurological diseases

Application of CRISPR genetic screens to investigate neurological diseases

The adoption of CRISPR-Cas9 technology for functional genetic screens has been a transformative advance. Due to its modular nature, this technology can be customized to address a myriad of questions. To date, pooled, genome-scale studies have uncovered genes responsible for survival, proliferation,...

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Main Authors: So, Raphaella W L (Author), Chung, Sai W (Author), Lau, Heather H C (Author), Watts, Jeremy J (Author), Gaudette, Erin (Author), Al-Azzawi, Zaid A M (Author), Bishay, Jossana (Author), Lin, Lilian T (Author), Joung, Julia (Author), Wang, Xinzhu (Author), Schmitt-Ulms, Gerold (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Broad Institute of MIT and Harvard (Contributor)
Format: Article
Language:English
Published: BioMed Central, 2020-07-08T20:31:05Z.
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