Hypoxia-inducible factor cell non-autonomously regulates C. elegans stress responses and behavior via a nuclear receptor

The HIF (hypoxia-inducible factor) transcription factor is the master regulator of the metazoan response to chronic hypoxia. In addition to promoting adaptations to low oxygen, HIF drives cytoprotective mechanisms in response to stresses and modulates neural circuit function. How most HIF targets ac...

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Bibliographic Details
Main Authors: Pender, Corinne Lenore (Author), Horvitz, Howard Robert (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), McGovern Institute for Brain Research at MIT (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd, 2020-07-07T19:36:28Z.
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