IKKβ slows Huntington's disease progression in R6/1 mice

IKKβ slows Huntington's disease progression in R6/1 mice

Neuroinflammation is an important contributor to neuronal pathology and death in neurodegenerative diseases and neuronal injury. Therapeutic interventions blocking the activity of the inflammatory kinase IKKβ, a key regulator of neuroinflammatory pathways, is protective in several animal models of n...

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Main Authors: Ochaba, Joseph (Author), Fote, Gianna (Author), Kachemov, Marketta (Author), Thein, Soe (Author), Yeung, Sylvia Y. (Author), Lau, Alice L. (Author), Hernandez, Sarah (Author), Lim, Ryan G. (Author), Casale, Malcolm (Author), Neel, Michael J. (Author), Monuki, Edwin S. (Author), Reidling, Jack (Author), Housman, David E (Author), Thompson, Leslie M. (Author), Steffan, Joan S. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2020-07-07T19:19:44Z.
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