Mammalian germ cells are determined after PGC colonization of the nascent gonad
Mammalian primordial germ cells (PGCs) are induced in the embryonic epiblast, before migrating to the nascent gonads. In fish, frogs, and birds, the germline segregates even earlier, through the action of maternally inherited germ plasm. Across vertebrates, migrating PGCs retain a broad developmenta...
Main Authors: | Nicholls, Peter K. (Author), Schorle, Hubert (Author), Naqvi, Sahin (Author), Hu, Yueh-Chiang (Author), Fan, Yuting (Author), Carmell, Michelle A. (Author), Page, David C. (Author) |
---|---|
Other Authors: | Whitehead Institute for Biomedical Research (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor) |
Format: | Article |
Language: | English |
Published: |
Proceedings of the National Academy of Sciences,
2020-05-07T14:20:52Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
<it>Dppa3 / Pgc7 / stella </it>is a maternal factor and is not required for germ cell specification in mice
by: Page David C, et al.
Published: (2004-02-01) -
Poised chromatin in the mammalian germ line
by: Lesch, B. J., et al.
Published: (2017) -
Dppa3 / Pgc7 / stellais a maternal factor and is not required for germ cell specification in mice
by: Bortvin, Alex, et al.
Published: (2010) -
Extra-gonadal germ cell tumor
by: A. ElRifai, et al.
Published: (2020-08-01) -
Gonadal germ cell tumors in children and adolescents
by: Giovanni Cecchetto
Published: (2014-01-01)