A Tumor Cell-Intrinsic Yin-Yang Determining Immune Evasion
Pancreatic adenocarcinoma (PDAC) is mostly refractory to immunotherapies. In this issue of Immunity, Li et al. (2018) generate a library of clonal PDAC tumors to examine the tumor-intrinsic features shaping the anti-tumor immune response and find that tumor cell-derived CXCL1 directly blunts T cell...
Main Authors: | Horton, Brendan (Author), Spranger, Stefani (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier BV,
2020-04-15T16:20:36Z.
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Subjects: | |
Online Access: | Get fulltext |
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