Incorporating Solvent-Dependent Kinetics To Design a Multistage, Continuous, Combined Cooling/Antisolvent Crystallization Process

Incorporating Solvent-Dependent Kinetics To Design a Multistage, Continuous, Combined Cooling/Antisolvent Crystallization Process

Combined cooling and antisolvent crystallization enables crystallization of many pharmaceutical products, but its process design typically neglects solvent composition influences on crystallization kinetics. This paper evaluates the influence of solvent-dependent nucleation and growth kinetics on th...

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Bibliographic Details
Main Authors: Schall, Jennifer M. (Author), Capellades Mendez, Gerard (Author), Mandur, Jasdeep S. (Author), Braatz, Richard D. (Author), Myerson, Allan S. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2020-02-28T16:31:07Z.
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