Copper Hydride Catalyzed Enantioselective Synthesis of Axially Chiral 1,3-Disubstituted Allenes
The general enantioselective synthesis of axially chiral disubstituted allenes from prochiral starting materials remains a long-standing challenge in organic synthesis. Here, we report an efficient enantio- and chemoselective copper hydride catalyzed semireduction of conjugated enynes to furnish 1,3...
Main Authors: | Bayeh-Romero, Liela (Author), Buchwald, Stephen Leffler (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry (Contributor) |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS),
2019-09-25T20:33:45Z.
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Subjects: | |
Online Access: | Get fulltext |
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