Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses

Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses

Mice engrafted with components of a human immune system have become widely-used models for studying aspects of human immunity and disease. However, a defined methodology to objectively measure and compare the quality of the human immune response in different models is lacking. Here, by taking advant...

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Bibliographic Details
Main Authors: Douam, Florian (Author), Hrebikova, Gabriela (Author), Fant, Bruno (Author), Leach, Robert (Author), Parsons, Lance (Author), Wang, Wei (Author), Gaska, Jenna M. (Author), Winer, Benjamin Y. (Author), Heller, Brigitte (Author), Ploss, Alexander (Author), Ziegler, Carly (Contributor), Shalek, Alexander K (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Ragon Institute of MGH, MIT and Harvard (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2019-03-07T15:34:44Z.
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