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|a dc
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|a Diaspro, Alberto
|e author
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|a Massachusetts Institute of Technology. Department of Biological Engineering
|e contributor
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|a Massachusetts Institute of Technology. Department of Chemistry
|e contributor
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|a Massachusetts Institute of Technology. Department of Mechanical Engineering
|e contributor
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|a Massachusetts Institute of Technology. Biological Engineering Accelerator Mass Spectrometry Lab
|e contributor
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|a Massachusetts Institute of Technology. Laser Biomedical Research Center
|e contributor
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|a Hosseini, Poorya
|e contributor
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|a Zhou, Renjie
|e contributor
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|a Kim, Yang-Hyo
|e contributor
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|a Peres, Chiara
|e contributor
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|a Kuang, Cuifang
|e contributor
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|a Yaqoob, Zahid
|e contributor
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|a So, Peter T. C.
|e contributor
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|a Hosseini, Poorya
|e author
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|a Zhou, Renjie
|e author
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|a Kim, Yang-Hyo
|e author
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1 |
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|a Peres, Chiara
|e author
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| 700 |
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|a Kuang, Cuifang
|e author
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|a Yaqoob, Zahid
|e author
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|a So, Peter T. C.
|e author
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| 245 |
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|a Pushing phase and amplitude sensitivity limits in interferometric microscopy
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| 260 |
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|b The Optical Society,
|c 2019-02-11T19:03:08Z.
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| 856 |
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|z Get fulltext
|u http://hdl.handle.net/1721.1/120330
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|a Sensitivity of the amplitude and phasemeasurements in interferometric microscopy is influenced by factors such as instrument design and environmental interferences. Through development of a theoretical framework followed by experimental validation, we show photon shot noise is often the limiting factor in interferometric microscopy measurements. Thereafter,wedemonstratehowa state-of-the-art camera with million-level electrons full well capacity can significantly reduce shot noise contribution resulting in a stability of optical path length down to a few picometers even in a near-common-path interferometer.
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|a National Institutes of Health (U.S.) (1R01EY017656-06)
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|a National Institutes of Health (U.S.) (1U01NS090438-01)
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|a National Institutes of Health (U.S.) (9P41EB015871-28)
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|a National Institutes of Health (U.S.) (DP3DK101024-01)
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| 520 |
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|a National Institutes of Health (U.S.) (1-R01HL121386-01)
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| 520 |
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|a National Institutes of Health (U.S.) (1R21NS091982-01)
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| 520 |
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|a National Institutes of Health (U.S.) (1U01CA202177-01)
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|a Hamamatsu Corporation
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|a Singapore-MIT Alliance
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|a Skolkovo Foundation
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|a Koch Institute for Integrative Cancer Research. Bridge Project Initiative
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|a Connecticut Children's Medical Center
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|a Samsung Advanced Institute of Technology
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7 |
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|a Article
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|t Optics Letters
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