Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota

Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota

Intestinal epithelial homeostasis is maintained by complex interactions among epithelial cells, commensal gut microorganisms, and immune cells. Disruption of this homeostasis is associated with disorders such as inflammatory bowel disease (IBD), but the mechanisms of this process are not clear. We i...

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Main Authors: Wellman, Alicia S. (Author), Metukuri, Mallikarjuna R. (Author), Kazgan, Nevzat (Author), Xu, Xiaojiang (Author), Xu, Qing (Author), Ren, Natalie S.X (Author), Shanahan, Michael T. (Author), Kang, Ashley (Author), Chen, Willa (Author), Azcarate-Peril, M. Andrea (Author), Gulati, Ajay S. (Author), Fargo, David C. (Author), Li, Xiaoling (Author), Guarente, Leonard Pershing (Contributor), Czopik, Agnieszka (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Czopik, Agnieszka K (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2018-11-08T15:44:27Z.
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