Epigenetic Modulation Using Small Molecules - Targeting Histone Acetyltransferases in Disease
Histone acetyltransferases (HATs) are epigenetic drivers that catalyze the acetyl transfer from acetyl-CoA to lysines of both histone and non-histone substrates and thereby induce transcription either by chromatin remodeling or direct transcription factor activation. Histone deacetylases (HDACs) con...
Main Authors: | , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Bentham Science,
2018-11-05T19:15:35Z.
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Subjects: | |
Online Access: | Get fulltext |