N-methyl d-Aspartate Channels Link Ammonia and Epithelial Cell Death Mechanisms in Helicobacter pylori Infection

Background & Aims: Helicobacter pylori infection is a risk factor for gastric cancer. Ammonia/ammonium (A/A) is a cytotoxin generated by H pylori that kills gastric epithelial cells. We investigated whether A/A cytotoxicity occurs by activating N-methyl d-aspartate (NMDA) channels, which results...

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Bibliographic Details
Main Authors: Seo, Ji Hye (Author), Peek, Richard M. (Author), Hagen, Susan J. (Author), Fox, James G (Contributor)
Other Authors: Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2018-09-06T15:59:58Z.
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