Next generation high throughput DNA damage detection platform for genotoxic compound screening

Methods for quantifying DNA damage, as well as repair of that damage, in a high-throughput format are lacking. Single cell gel electrophoresis (SCGE; comet assay) is a widely-used method due to its technical simplicity and sensitivity, but the standard comet assay has limitations in reproducibility...

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Bibliographic Details
Main Authors: Sykora, Peter (Author), Witt, Kristine L. (Author), Revanna, Pooja (Author), Smith-Roe, Stephanie L. (Author), Dismukes, Jonathan (Author), Lloyd, Donald G. (Author), Sobol, Robert W. (Author), Engelward, Bevin P (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2018-08-28T19:20:04Z.
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