An Integrin-Linked Machinery of Cytoskeletal Regulation that Enables Experimental Tumor Initiation and Metastatic Colonization
Recently extravasated metastatic cancer cells use the Rif/mDia2 actin-nucleating/polymerizing machinery in order to extend integrin β1-containing, filopodium-like protrusions (FLPs), which enable them to interact productively with the surrounding extracellular matrix; this process governs the initia...
Main Authors: | Shibue, Tsukasa (Contributor), Brooks, Mary W (Contributor), Weinberg, Robert A (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Ludwig Center for Molecular Oncology (Massachusetts Institute of Technology) (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2018-07-12T18:22:36Z.
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Subjects: | |
Online Access: | Get fulltext |
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