Cancer cells exhibit clonal diversity in phenotypic plasticity
Phenotypic heterogeneity in cancers is associated with invasive progression and drug resistance. This heterogeneity arises in part from the ability of cancer cells to switch between phenotypic states, but the dynamics of this cellular plasticity remain poorly understood. Here we apply DNA barcodes t...
Main Authors: | Mathis, Robert Austin (Contributor), Sokol, Ethan Samuel (Contributor), Gupta, Piyush (Contributor) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor) |
Format: | Article |
Language: | English |
Published: |
The Royal Society,
2018-06-21T14:56:52Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Cancer cells exhibit clonal diversity in phenotypic plasticity
by: Robert Austin Mathis, et al.
Published: (2017-01-01) -
The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition
by: Feng, Yu-xiong, et al.
Published: (2018) -
The relative importance of genetic diversity and phenotypic plasticity in determining invasion success of a clonal weed in the USA and China
by: Yupeng eGeng, et al.
Published: (2016-02-01) -
Perturbation-Expression Analysis Identifies RUNX1 as a Regulator of Human Mammary Stem Cell Differentiation
by: Sanduja, Sandhya, et al.
Published: (2015) -
Phenotypic plasticity influences the success of clonal propagation in industrial pharmaceutical Cannabis sativa.
by: Lesley G Campbell, et al.
Published: (2019-01-01)