Aneuploidy Causes Non-genetic Individuality
Phenotypic variability is a hallmark of diseases involving chromosome gains and losses, such as Down syndrome and cancer. Allelic variances have been thought to be the sole cause of this heterogeneity. Here, we systematically examine the consequences of gaining and losing single or multiple chromoso...
Main Authors: | Ricci-Tam, Chiara (Author), Hua, Bo (Author), Springer, Michael (Author), Brennan, Christopher M (Contributor), Moomau, Christine Anne (Contributor), Hsu, Pei-Hsin (Contributor), Silberman, Rebecca Estelle (Contributor), Amon, Angelika B. (Contributor), Thorburn, Rebecca Ruth (Author) |
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Other Authors: | Koch Institute for Integrative Cancer Research at MIT (Contributor), Beach, Rebecca Ruth (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier BV,
2018-06-06T18:12:34Z.
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Subjects: | |
Online Access: | Get fulltext |
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