Genetic circuit characterization and debugging using RNA‐seq

Genetic circuits implement computational operations within a cell. Debugging them is difficult because their function is defined by multiple states (e.g., combinations of inputs) that vary in time. Here, we develop RNA‐seq methods that enable the simultaneous measurement of: (i) the states of intern...

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Bibliographic Details
Main Authors: Gorochowski, Thomas Edward (Contributor), Espah Borujeni, Amin (Contributor), Park, YongJin (Contributor), Nielsen, Alec Andrew (Contributor), Der, Bryan S. (Contributor), Gordon, David B (Contributor), Voigt, Christopher A. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2018-03-30T18:02:40Z.
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