A light- and calcium-gated transcription factor for imaging and manipulating activated neurons

A light- and calcium-gated transcription factor for imaging and manipulating activated neurons

Activity remodels neurons, altering their molecular, structural, and electrical characteristics. To enable the selective characterization and manipulation of these neurons, we present FLARE, an engineered transcription factor that drives expression of fluorescent proteins, opsins, and other genetica...

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Bibliographic Details
Main Authors: Wang, Wenjing (Contributor), Wildes, Craig P (Author), Pattarabanjird, Tanyaporn (Contributor), Sanchez, Mateo I (Author), Glober, Gordon F (Author), Matthews, Gillian A (Author), Tye, Kay M (Author), Ting, Alice Y (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2018-01-12T16:00:07Z.
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