Divergent unprotected peptide macrocyclisation by palladium-mediated cysteine arylation
Macrocyclic peptides are important therapeutic candidates due to their improved physicochemical properties in comparison to their linear counterparts. Here we detail a method for a divergent macrocyclisation of unprotected peptides by crosslinking two cysteine residues with bis-palladium organometal...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Royal Society of Chemistry (RSC),
2018-01-10T15:31:37Z.
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| Subjects: | |
| Online Access: | Get fulltext |