Chromosome Compaction by Active Loop Extrusion
During cell division, chromosomes are compacted in length by more than a 100-fold. A wide range of experiments demonstrated that in their compacted state, mammalian chromosomes form arrays of closely stacked consecutive ∼100 kb loops. The mechanism underlying the active process of chromosome compact...
Main Authors: | Marko, John F (Author), Goloborodko, Anton (Contributor), Mirny, Leonid A (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2017-12-19T14:32:06Z.
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Subjects: | |
Online Access: | Get fulltext |
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