Deletion of ribosomal protein genes is a common vulnerability in human cancer, especially in concert with

Deletion of ribosomal protein genes is a common vulnerability in human cancer, especially in concert with

Heterozygous inactivating mutations in ribosomal protein genes (RPGs) are associated with hematopoietic and developmental abnormalities, activation of p53, and altered risk of cancer in humans and model organisms. Here we performed a large‐scale analysis of cancer genome data to examine the frequenc...

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Bibliographic Details
Main Authors: Ajore, Ram (Author), Raiser, David (Author), McConkey, Marie (Author), Jöud, Magnus (Author), Boidol, Bernd (Author), Mar, Brenton (Author), Saksena, Gordon (Author), Weinstock, David M (Author), Armstrong, Scott (Author), Ellis, Steven R (Author), Ebert, Benjamin L (Contributor), Nilsson, Bjorn (Contributor)
Other Authors: Broad Institute of MIT and Harvard (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2017-06-15T14:44:21Z.
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