Differential selective pressure alters rate of drug resistance acquisition in heterogeneous tumor populations
Recent drug discovery and development efforts have created a large arsenal of targeted and chemotherapeutic drugs for precision medicine. However, drug resistance remains a major challenge as minor pre-existing resistant subpopulations are often found to be enriched at relapse. Current drug design h...
| Main Authors: | , , , , |
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| Other Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group,
2017-06-12T13:57:13Z.
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| Subjects: | |
| Online Access: | Get fulltext |