Quantifying intracellular protein binding thermodynamics during mechanotransduction based on FRET spectroscopy

Quantifying intracellular protein binding thermodynamics during mechanotransduction based on FRET spectroscopy

Mechanical force modulates myriad cellular functions including migration, alignment, proliferation, and gene transcription. Mechanotransduction, the transmission of mechanical forces and its translation into biochemical signals, may be mediated by force induced protein conformation changes, subseque...

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Bibliographic Details
Main Authors: Mofrad, Mohammad R.K (Author), Abdul Rahim, Nur Aida (Contributor), Pelet, Serge (Contributor), So, Peter T. C. (Contributor), Kamm, Roger Dale (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. Laser Biomedical Research Center (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-06-02T17:38:37Z.
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