Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated subjects

Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated subjects

Background Peanut oral immunotherapy (PNOIT) induces persistent tolerance to peanut in a subset of patients and induces specific antibodies that might play a role in clinical protection. However, the contribution of induced antibody clones to clinical tolerance in PNOIT is unknown. Objective We hypo...

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Main Authors: Calatroni, Agustin (Author), Tadigotla, Vasisht R. (Author), Ruiter, Bert (Author), Ma, Alex (Author), Moon, James (Author), Shreffler, Wayne G. (Author), Patil, Sarita (Contributor), Ogunniyi, Adebola Oluwakayode (Contributor), Love, John C (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-05-30T19:44:54Z.
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