Molecular Criteria for Defining the Naive Human Pluripotent State

Molecular Criteria for Defining the Naive Human Pluripotent State

Recent studies have aimed to convert cultured human pluripotent cells to a naive state, but it remains unclear to what extent the resulting cells recapitulate in vivo naive pluripotency. Here we propose a set of molecular criteria for evaluating the naive human pluripotent state by comparing it to t...

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Main Authors: Theunissen, Thorold W (Author), Friedli, Marc (Author), He, Yupeng (Author), Planet, Evarist (Author), O'Neil, Ryan C (Author), Markoulaki, Styliani (Author), Pontis, Julien (Author), Wang, Haoyi (Author), Iouranova, Alexandra (Author), Imbeault, Michaël (Author), Duc, Julien (Author), Cohen, Malkiel A (Author), Wert, Katherine J (Author), Castanon, Rosa (Author), Zhang, Zhuzhu (Author), Huang, Yanmei (Author), Nery, Joseph R (Author), Drotar, Jesse (Author), Lungjangwa, Tenzin (Author), Trono, Didier (Author), Ecker, Joseph R (Author), Jaenisch, Rudolf (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-05-15T13:27:01Z.
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