Building Robust Transcriptomes with Master Splicing Factors

Coherent splicing networks arise from many discrete splicing decisions regulated in unison. Here, we examine the properties of robust, context-specific splicing networks. We propose that a subset of key splicing regulators, or "master splicing factors," respond to environmental cues to est...

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Bibliographic Details
Main Authors: Sharp, Phillip A. (Contributor), Jangi, Mohini Rohit (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-04-07T17:21:04Z.
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