Phosphotyrosine Signaling Analysis in Human Tumors Is Confounded by Systemic Ischemia-Driven Artifacts and Intra-Specimen Heterogeneity

Phosphotyrosine Signaling Analysis in Human Tumors Is Confounded by Systemic Ischemia-Driven Artifacts and Intra-Specimen Heterogeneity

Tumor protein phosphorylation analysis may provide insight into intracellular signaling networks underlying tumor behavior, revealing diagnostic, prognostic or therapeutic information. Human tumors collected by The Cancer Genome Atlas program potentially offer the opportunity to characterize activat...

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Bibliographic Details
Main Authors: Slebos, R. J. C. (Author), Shaddox, K. (Author), Wiles, K. (Author), Washington, M. K. (Author), Herline, A. J. (Author), Levine, D. A. (Author), Liebler, D. C. (Author), Gajadhar, Aaron (Contributor), Johnson, Hannah (Contributor), White, Forest M. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), White, Forest M (Contributor)
Format: Article
Language:English
Published: American Association for Cancer Research, 2017-03-24T14:46:25Z.
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