Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening
Deregulation of autophagy has been linked to multiple degenerative diseases and cancer, thus the identification of novel autophagy regulators for potential therapeutic intervention is important. To meet this need, we developed a high content image-based short hairpin RNA screen monitoring levels of...
Main Authors: | Strohecker, A M (Author), Joshi, S (Author), Abraham, R T (Author), White, E (Author), Possemato, Richard (Contributor), Sabatini, David (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor) |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2017-01-30T16:04:02Z.
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Subjects: | |
Online Access: | Get fulltext |
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